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Generation of excessive free radicals coupled with depletion of cellular redox defense system disrupts the normal redox cycle, resulting in enhanced OS

LOOPER: A molecular mechanics-based algorithm for protein loop prediction

Biotechnol Lett 26:415417

His findings indicate that waking up in the middle of the night may be a normal physiological event, not a sleep disorder

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In addition, Nrf2 induces the expression of SLC7A11, which promotes cystine uptake and supports GSH production, thereby reinforcing the cellular defense against ferroptosis ( Nrf2 also plays a role in iron metabolism, which is closely linked to ferroptotic susceptibility